Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844597 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL11224609 | 0.90 | MAOB (0.59) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL11224607 | 0.90 | MAOB (0.59) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL11224613 | 0.90 | MAOB (0.59) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL600336 | 0.83 | MAOB (0.55) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL600337 | 0.83 | MAOB (0.55) | MEN1KMT2AMAPTNPSR1MAOB | |
| SCHEMBL1758388 | 0.82 | AKR1C3 (0.42) | MEN1KMT2AAKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL1758384 | 0.82 | AKR1C3 (0.42) | MEN1KMT2AAKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL4455663 | 0.82 | AKR1C3 (0.42) | MEN1KMT2AAKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL6285284 | 0.78 | MAOB (0.50) | MEN1KMT2AMAPTNPSR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, ELAVL1, EPCAM | MEN1 835/4885KMT2A 4115/4885MAPT 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.