SCHEMBL600337

SCHEMBL600337

O=C(O)C(=Cc1ccccc1[N+](=O)[O-])c1cccc(C(=Cc2ccccc2[N+](=O)[O-])C(=O)O)c1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.55
MAPT P10636 6/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
AKR1C1 Q04828 1/20 0.47
ALDH1A1 P00352 2/20 0.46
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
LMNA P02545 1/20 0.44
ATM Q13315 1/20 0.44
PKM P14618 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600336 1.00 MAOB (0.55) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL11224609 0.92 MAOB (0.59) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL11224613 0.92 MAOB (0.59) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL11224607 0.92 MAOB (0.59) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL6285273 0.92 MAOB (0.50) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL6285284 0.92 MAOB (0.50) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL6277898 0.87 MAOB (0.46) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL6277895 0.87 MAOB (0.46) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL11227620 0.84 MAOB (0.56) MAOBMAPTNPSR1MEN1KMT2A
SCHEMBL11227618 0.84 MAOB (0.56) MAOBMAPTNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001839-B Particles for electrophoretic displays 默克专利股份有限公司 2021-01-15 CN disclosed
CN-107108818-B Particles for electrophoretic displays 默克专利股份有限公司 2021-01-01 CN disclosed
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 US disclosed
US-10428220-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-01 US disclosed
EP-2393849-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-3234042-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-2834705-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS COMPRISING A CORE AND A RANDOM-COPOLYMER COATING MERCK PATENT GMBH (DE) 2018-12-05 EP disclosed
US-10126625-B2 Particles for electrophoretic displays comprising a core and a random-copolymer coating MERCK PATENT GMBH (DE) 2018-11-13 US disclosed
EP-2850116-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-04-18 EP disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-20110310462-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-22 US disclosed
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-15 US disclosed
EP-2393850-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393851-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393848-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089060-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089058-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH, (DE) 2010-08-12 WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE MAOB 2932/4885MAPT 3084/4885NPSR1 1731/4885
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, IK, SELP MAOB 2463/4885MAPT 2386/4885NPSR1 2443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.