SCHEMBL37783

SCHEMBL37783

CCCCCCCCCCCCCCCCCCNC(C)(C)CC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 11/20 0.52
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
THRB P10828 1/20 0.40
PPARA Q07869 2/20 0.37
GBA1 P04062 1/20 0.35
CASP2 P42575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3373268 1.00 EPHX1 (0.52) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL37597 1.00 EPHX1 (0.52) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL10589508 1.00 EPHX1 (0.52) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL7110706 1.00 EPHX1 (0.52) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL3369909 1.00 EPHX1 (0.52) EPHX1TSHRALDH1A1ADH1BADH1C
Hydrochloric Acid SCHEMBL8041489 0.98 EPHX1 (0.50) EPHX1TSHRALDH1A1ADH1BADH1C
Bromide SCHEMBL1459266 0.98 EPHX1 (0.50) EPHX1TSHRALDH1A1ADH1BADH1C
Hydrochloric Acid SCHEMBL28937648 0.98 EPHX1 (0.50) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL3370320 0.97 EPHX1 (0.48) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL3369009 0.90 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9809717-B2 Antimicrobial-coated medical articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-11-07 US disclosed
EP-2576471-B1 ANTIMICROBIAL COATED MEDICAL ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2017-10-25 EP disclosed
EP-2576472-B1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2016-03-23 EP disclosed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US disclosed
US-20150024019-A1 ANTIMICROBIAL-COATED MEDICAL ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2015-01-22 US disclosed
EP-2576472-A2 ANTIMICROBIAL COATINGS 3M Innovative Properties Company (US) 2013-04-10 EP disclosed
EP-2576471-A2 ANTIMICROBIAL COATED MEDICAL ARTICLES 3M Innovative Properties Company (US) 2013-04-10 EP disclosed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US disclosed
WO-2011150103-A2 ANTIMICROBIAL–COATED MEDICAL ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-01 WO disclosed
WO-2011150001-A2 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN EPHX1 3972/4885TSHR 4723/4885ALDH1A1 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.