Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760074 | 0.82 | — | — | |
| SCHEMBL27646 | 0.82 | — | — | |
| SCHEMBL134032 | 0.82 | — | — | |
| Benzene SCHEMBL6380470 | 0.80 | ALDH1A1 (0.73) | ALDH1A1TSHRMEN1KMT2A | |
| Biphenyl SCHEMBL3084965 | 0.77 | ALDH1A1 (0.67) | ALDH1A1 | |
| Methane SCHEMBL7940021 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL2510522 | 0.76 | — | — | |
| Methane SCHEMBL6180360 | 0.71 | — | — | |
| SCHEMBL14973466 | 0.67 | — | — | |
| SCHEMBL20193393 | 0.67 | ALDH1A1 (0.89) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858837-B1 | PROCESS FOR THE PRODUCTION OF 2-(2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| US-7514584-B2 | Process for the production of 2(2-aminophenyl)-bicylopropane derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20080161610-A1 | Process For the Production of 2(2-Aminophenyl)-Bicylopropane Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| EP-1858837-A1 | PROCESS FOR THE PRODUCTION OF 2-(2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | Syngeta Participations AG (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006087223-A1 | PROCESS FOR THE PRODUCTION OF 2- (2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087222-A1 | PROCESS FOR THE PRODUCTION OF NITROBENZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087221-A1 | PROCESS FOR THE PRODUCTION OF NITROBENZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161610-A1 | Process For the Production of 2(2-Aminophenyl)-Bicylopropane Derivatives | CYP1B1, CYP4B1, MAOB | ALDH1A1 738/4885TP53 4752/4885TSHR 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.