SCHEMBL37788

SCHEMBL37788

[c]1ccccc1Oc1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 7/20 0.41
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 5/20 0.39
GAA P10253 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 2/20 0.39
KCNA3 P22001 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 2/20 0.38
PGR P06401 1/20 0.38
PTGS1 P23219 1/20 0.38
MAPK1 P28482 1/20 0.38
ESRRA P11474 1/20 0.38
HTR1D P28221 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
SLC6A4 P31645 1/20 0.37
HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4719643 0.84 NQO1 (0.35) HTR1BALDH1A1KDM4EGAAMAPT
SCHEMBL10965997 0.82 KDM4E (0.35) ALDH1A1KDM4EL3MBTL1MAPTMAPK1
SCHEMBL5402131 0.80 HTR1B (0.48) HTR1BALDH1A1KDM4EGAAL3MBTL1
SCHEMBL6538510 0.80 HTR1B (0.47) HTR1BALDH1A1KDM4EHPGDKCNA3
SCHEMBL737533 0.79 ALDH1A1 (0.46) HTR1BALDH1A1KDM4EGAAL3MBTL1
SCHEMBL6539578 0.78 HTR1B (0.57) HTR1BKCNA3TDP1HTR1DKMT2A
SCHEMBL29577853 0.77 HTR1B (0.54) HTR1BALDH1A1KDM4EGAAL3MBTL1
SCHEMBL442767 0.77 HTR1B (0.54) HTR1BALDH1A1KDM4EGAAL3MBTL1
Lithium SCHEMBL6571336 0.75 HTR1B (0.52) HTR1BALDH1A1KDM4EGAAL3MBTL1
Methane SCHEMBL10959030 0.75 HTR1B (0.52) HTR1BALDH1A1KDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005589-A Synthesis method for preparing 6-methoxy dihydropyranone by substituted 2, 5-dihydro furanmethanol in one step 大连理工大学 2024-05-10 CN claimed
CN-114105993-B Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2023-03-10 CN claimed
CN-114105993-A Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2022-03-01 CN claimed
CN-109942553-B Synthesis and conversion method of chiral 3,4, 6-trisubstituted tetrahydro 2H-pyran-2-one compound 大连理工大学 2020-09-29 CN claimed
CN-109942553-A A kind of synthesis of tri- substituted-tetrahydro 2H- pyran-2-one compound of chirality 3,4,6- and its method for transformation 大连理工大学 2019-06-28 CN claimed
EP-1423387-B1 PHOTOCHROMIC BIS-NAPHTHOPYRAN COMPOUNDS AND METHODS FOR THEIR MANUFACTURE ESSILOR INT (FR) 2010-03-17 EP claimed
US-20050123778-A1 Polyolefins made by catalyst comprising a noncoordinating anion and articles comprising them EXXONMOBIL CHEMICAL PATENTS INC. 2005-06-09 US claimed
EP-1406761-A2 POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2004-04-14 EP claimed
WO-2003000740-A2 POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-01-03 WO claimed
EP-0574355-B1 Phosphinyloxy propanaminium inner salt derivatives CIBA GEIGY AG (CH) 1997-08-13 EP claimed
US-5516767-A PRODRUG AS HYPOGLYCEMIC AGENT SANDOZ LTD. (CH) 1996-05-14 US claimed
US-5412137-A Hypoglycemic agents SANDOZ LTD. (CH) 1995-05-02 US claimed
EP-0574355-A1 Phosphinyloxy propanaminium inner salt derivatives SANDOZ LTD. (CH) 1993-12-15 EP claimed
EP-0282096-A2 Poly(dinaphthyl arylene ether)and preparation thereof THE B.F. GOODRICH COMPANY (US) 1988-09-14 EP claimed
US-4675316-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1987-06-23 US claimed
CN-118005589-A Synthesis method for preparing 6-methoxy dihydropyranone by substituted 2, 5-dihydro furanmethanol in one step 大连理工大学 2024-05-10 CN disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
US-4046656-A Photochlorination process for methyl aromatic compounds THE DOW CHEMICAL COMPANY (US) 1977-09-06 US disclosed
US-4025341-A CONDENSATION POLYMER OF A TERTIARY AROMATIC AMINE, A SENSITIZER, AND A CARBONYL COMPOUND EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed