SCHEMBL37789

SCHEMBL37789

[c]1ccc(Oc2cccc3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
LMNA P02545 2/20 0.44
MITF O75030 1/20 0.44
POLB P06746 1/20 0.44
KCNA3 P22001 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
SIRT3 Q9NTG7 1/20 0.43
MAPT P10636 3/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTR1B P28222 5/20 0.42
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27705785 0.86 KCNA3 (0.56) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL2078871 0.86 L3MBTL1 (0.54) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL4719645 0.85 NQO1 (0.37) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL441860 0.84 KCNA3 (0.58) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL29860318 0.84 KCNA3 (0.58) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL28029061 0.80 KCNA3 (0.44) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL386120 0.80 KCNA3 (0.40) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL29148791 0.80 L3MBTL1 (0.50) MEN1KMT2AL3MBTL1LMNAMITF
SCHEMBL6538513 0.79 KCNA3 (0.54) MEN1KMT2AKCNA3HPGDHTR1B
SCHEMBL442767 0.79 HTR1B (0.54) MEN1KMT2AL3MBTL1KCNA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005589-A Synthesis method for preparing 6-methoxy dihydropyranone by substituted 2, 5-dihydro furanmethanol in one step 大连理工大学 2024-05-10 CN claimed
CN-114105993-B Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2023-03-10 CN claimed
CN-114105993-A Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2022-03-01 CN claimed
CN-109942553-B Synthesis and conversion method of chiral 3,4, 6-trisubstituted tetrahydro 2H-pyran-2-one compound 大连理工大学 2020-09-29 CN claimed
CN-109942553-A A kind of synthesis of tri- substituted-tetrahydro 2H- pyran-2-one compound of chirality 3,4,6- and its method for transformation 大连理工大学 2019-06-28 CN claimed
CN-101400640-B Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction NIPPON SODA CO 2013-05-08 CN claimed
EP-1423387-B1 PHOTOCHROMIC BIS-NAPHTHOPYRAN COMPOUNDS AND METHODS FOR THEIR MANUFACTURE ESSILOR INT (FR) 2010-03-17 EP claimed
CN-101516860-A Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors NOVARTIS AG (CH) 2009-08-26 CN claimed
US-20050123778-A1 Polyolefins made by catalyst comprising a noncoordinating anion and articles comprising them EXXONMOBIL CHEMICAL PATENTS INC. 2005-06-09 US claimed
EP-1406761-A2 POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2004-04-14 EP claimed
WO-2003000740-A2 POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-01-03 WO claimed
CN-1039326-C Phosphinyloxy propanaminium inner salt derivatives SANDOZ LTD (CH) 1998-07-29 CN claimed
EP-0574355-B1 Phosphinyloxy propanaminium inner salt derivatives CIBA GEIGY AG (CH) 1997-08-13 EP claimed
US-5516767-A PRODRUG AS HYPOGLYCEMIC AGENT SANDOZ LTD. (CH) 1996-05-14 US claimed
US-5412137-A Hypoglycemic agents SANDOZ LTD. (CH) 1995-05-02 US claimed
CN-1086217-A The derivative of Phosphinyloxy propanaminium inner salt SANDOZ LTD (CH) 1994-05-04 CN claimed
EP-0574355-A1 Phosphinyloxy propanaminium inner salt derivatives SANDOZ LTD. (CH) 1993-12-15 EP claimed
US-4675316-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1987-06-23 US claimed
CN-118005589-A Synthesis method for preparing 6-methoxy dihydropyranone by substituted 2, 5-dihydro furanmethanol in one step 大连理工大学 2024-05-10 CN disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed