Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775912 | 0.83 | KCNH2 (0.36) | KCNH2LMNAGAAHTTSLC2A1 | |
| SCHEMBL5318472 | 0.81 | KCNH2 (0.37) | KCNH2LMNASLC2A1CCR3MTNR1B | |
| SCHEMBL5254666 | 0.75 | KCNH2 (0.57) | KCNH2SLC2A1 | |
| SCHEMBL3779227 | 0.74 | KCNH2 (0.51) | KCNH2LMNAGAAHTTSLC2A1 | |
| SCHEMBL3775094 | 0.74 | KCNH2 (0.53) | KCNH2LMNAGAAHTTSLC2A1 | |
| SCHEMBL3779200 | 0.73 | SLC2A1 (0.47) | KCNH2LMNAGAAHTTSLC2A1 | |
| SCHEMBL3780005 | 0.73 | KCNH2 (0.56) | KCNH2LMNAHTTSLC2A1MAPT | |
| SCHEMBL3775100 | 0.72 | KCNH2 (0.36) | KCNH2LMNAGAAHTTSLC2A1 | |
| SCHEMBL3772117 | 0.72 | SLC2A1 (0.54) | KCNH2SLC2A1CCR3MTNR1BMTNR1A | |
| SCHEMBL3775540 | 0.71 | SLC2A1 (0.42) | KCNH2LMNAGAAHTTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | KCNH2 3216/4885LMNA 1376/4885GAA 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.