Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.55 |
| ▸ | ABL1 | P00519 | 7/20 | 0.55 |
| ▸ | RET | P07949 | 7/20 | 0.53 |
| ▸ | KDR | P35968 | 5/20 | 0.53 |
| ▸ | LCK | P06239 | 3/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.53 |
| ▸ | FYN | P06241 | 3/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.53 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | YES1 | P07947 | 2/20 | 0.53 |
| ▸ | LYN | P07948 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | FRK | P42685 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30071096 | 0.85 | SRC (0.55) | SRCABL1RETKDRLCK | |
| SCHEMBL20874994 | 0.85 | SRC (0.55) | SRCABL1RETKDRLCK | |
| SCHEMBL19476926 | 0.81 | SRC (0.51) | SRCABL1RETKDRLCK | |
| SCHEMBL30071219 | 0.81 | SRC (0.51) | SRCABL1RETKDRLCK | |
| SCHEMBL20886319 | 0.79 | SRC (0.49) | SRCABL1RETKDRLCK | |
| SCHEMBL13019650 | 0.79 | SRC (0.64) | SRCABL1RETKDRLCK | |
| SCHEMBL13019696 | 0.77 | SRC (0.73) | SRCABL1RETKDRLCK | |
| SCHEMBL23055859 | 0.76 | SRC (0.58) | SRCABL1RETKDRLCK | |
| SCHEMBL22521563 | 0.76 | KDM4E (0.63) | SRCABL1RETKDRLCK | |
| SCHEMBL3782929 | 0.76 | SRC (0.58) | SRCABL1RETKDRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | SRC 1332/4885ABL1 1725/4885RET 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.