Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.62 |
| ▸ | ABL1 | P00519 | 8/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
| ▸ | LCK | P06239 | 3/20 | 0.54 |
| ▸ | TEK | Q02763 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.52 |
| ▸ | FYN | P06241 | 4/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.52 |
| ▸ | CSK | P41240 | 3/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019906 | 0.94 | SRC (0.56) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019908 | 0.90 | SRC (0.60) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019974 | 0.89 | PIK3CD (0.56) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019978 | 0.88 | SRC (0.52) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019878 | 0.87 | SRC (0.64) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019916 | 0.87 | KDM4E (0.64) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019879 | 0.87 | SRC (0.58) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019898 | 0.87 | SRC (0.50) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019876 | 0.87 | SRC (0.63) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019923 | 0.86 | KDM4E (0.53) | SRCABL1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2009062118-A2 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | SRC 1332/4885ABL1 1725/4885PIK3CD 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.