⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396675 | 0.78 | — | — | |
| SCHEMBL27696111 | 0.76 | — | — | |
| SCHEMBL22397156 | 0.69 | KMT2A (0.42) | — | |
| SCHEMBL5912729 | 0.67 | — | — | |
| SCHEMBL8007269 | 0.65 | TSHR (0.36) | — | |
| SCHEMBL584416 | 0.63 | TSHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL7212773 | 0.62 | BLM (0.40) | — | |
| SCHEMBL3396869 | 0.61 | TSHR (0.36) | — | |
| SCHEMBL17897341 | 0.60 | — | — | |
| SCHEMBL6053024 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| WO-2022169248-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | 주식회사 엘지화학 | 2022-08-11 | — | — | WO | disclosed |
| CN-104803916-B | Hete rocyclic derivatives as SARM (SARMS) | 詹森药业有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-103052640-B | Furopyridine Derivatives | 默克专利股份公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103565653-B | Substituted pyrazolone compound as well as using method and application of pyrazolone compound | 广东东阳光药业有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-104803916-A | Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms) | JANSSEN PHARMACEUTICA NV | 2015-07-29 | — | — | CN | disclosed |
| CN-103755700-B | A kind of pyrazol acid amide compounds and uses thereof | QINGDAO UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-101415710-B | Bicyclic imidazole or thiadiazole heterocycles useful as selective androgen receptor modulators | JANSSEN PHARMACEUTICA NV | 2013-08-21 | — | — | CN | disclosed |
| CN-101415419-B | Novel imidazolopyrazole derivatives useful as selective androgen receptor modulators | JANSSEN PHARMACEUTICA NV | 2012-06-13 | — | — | CN | disclosed |
| EP-2408300-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd (CN) | 2012-01-25 | — | — | EP | disclosed |
| US-20100022529-A1 | AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET | ELI LILLY AND COMPANY | 2010-01-28 | — | — | US | disclosed |
| CN-101415710-A | Bicyclic imidazole or thiadiazole heterocycles useful as selective androgen receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-22 | — | — | CN | disclosed |
| CN-101103003-A | Novel heterocyclic derivatives as Selective Androgen Receptor Modulators (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2008-01-09 | — | — | CN | disclosed |
| WO-2007026215-A1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING? THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| CN-1582274-A | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | WARNER LAMBERT CO (US) | 2005-02-16 | — | — | CN | disclosed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |