Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789231 | 0.74 | CPA1 (0.52) | CPA1ALDH1A1TSHR | |
| SCHEMBL18463625 | 0.72 | CPA1 (0.54) | CPA1TSHR | |
| SCHEMBL4212444 | 0.71 | — | — | |
| SCHEMBL3278706 | 0.70 | CPA1 (0.44) | CPA1ALDH1A1TSHR | |
| SCHEMBL1170344 | 0.70 | — | — | |
| SCHEMBL13567336 | 0.68 | CPA1 (0.55) | CPA1TSHR | |
| SCHEMBL1116709 | 0.68 | CPA1 (0.55) | CPA1ALDH1A1TSHR | |
| SCHEMBL16884566 | 0.67 | CPA1 (0.69) | CPA1 | |
| SCHEMBL13007945 | 0.67 | CPA1 (0.48) | CPA1ALDH1A1TSHR | |
| SCHEMBL13007954 | 0.67 | CPA1 (0.48) | CPA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395573-B | Process for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2014-05-07 | — | — | CN | disclosed |
| CN-103467443-A | Process for production of 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2013-12-25 | — | — | CN | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| CN-102395573-A | Process for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2012-03-28 | — | — | CN | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | CBR3, CYP2E1, SULT2A1 | CPA1 3923/4885ALDH1A1 201/4885TSHR 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.