Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708025 | 0.83 | RAB9A (0.65) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL13263729 | 0.77 | RAB9A (0.73) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL20565707 | 0.76 | RAB9A (0.41) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL3708557 | 0.74 | RAB9A (0.54) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL3702396 | 0.73 | KMT2A (0.64) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL23104339 | 0.73 | KDM4E (0.56) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL1244741 | 0.73 | AXL (0.43) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL20565659 | 0.73 | RAB9A (0.39) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL17447627 | 0.73 | MAPT (0.39) | RAB9AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL13304717 | 0.73 | RAB9A (0.42) | RAB9AMAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086040-A1 | PYRAZOLO-PYRIMIDINES FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-08-05 | — | — | WO | disclosed |