SCHEMBL3780552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3780913	0.85	L3MBTL1 (0.34)	CACNA1BCYP19A1NAAAEPHX1HSD11B1
	SCHEMBL3780890	0.85	L3MBTL1 (0.34)	CACNA1BCYP19A1NAAAEPHX1HSD11B1
	SCHEMBL3805536	0.85	L3MBTL1 (0.34)	CACNA1BCYP19A1NAAAEPHX1HSD11B1
	SCHEMBL3769068	0.83	CACNA1B (0.31)	CACNA1B
	SCHEMBL13061518	0.83	CACNA1B (0.31)	CACNA1B
	SCHEMBL21685040	0.82	TDP1 (0.37)	HDAC1HDAC6TDP1
	SCHEMBL13007474	0.82	TDP1 (0.37)	HDAC1HDAC6TDP1
	SCHEMBL20753403	0.79	TDP1 (0.38)	HDAC1HDAC6TDP1
	SCHEMBL28383245	0.79	TDP1 (0.38)	HDAC1HDAC6TDP1
	SCHEMBL17309877	0.78	TDP1 (0.39)	HDAC1HDAC6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.