Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 7/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780444 | 0.88 | MAPT (0.47) | MAPTAKR1C3CYP2C9RXRARXRB | |
| SCHEMBL3785121 | 0.86 | MAPT (0.45) | MAPTAKR1C3CYP2C9RXRARXRB | |
| SCHEMBL3786632 | 0.81 | MAPT (0.41) | MAPTAKR1C3CYP2C9RXRARXRB | |
| SCHEMBL3781076 | 0.79 | CYP2C9 (0.40) | MAPTAKR1C3CYP2C9RXRARXRB | |
| SCHEMBL8406891 | 0.77 | MAPT (0.57) | MAPTAKR1C3CYP2C9RXRARXRB | |
| SCHEMBL3791370 | 0.77 | CYP2C9 (0.41) | MAPTAKR1C3CYP2C9ALDH1A1 | |
| SCHEMBL3791372 | 0.76 | MAPT (0.36) | MAPTAKR1C3PPARGALDH1A1 | |
| SCHEMBL3792031 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL3786964 | 0.75 | CYP2C9 (0.40) | CYP2C9ALDH1A1 | |
| SCHEMBL8357936 | 0.74 | MAPT (0.54) | MAPTAKR1C3CYP2C9RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183540-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2010-07-22 | — | — | US | disclosed |