Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519208 | 0.87 | P2RX7 (0.40) | P2RX7PDE10A | |
| SCHEMBL519137 | 0.87 | P2RX7 (0.40) | P2RX7PDE10A | |
| SCHEMBL519474 | 0.84 | PDE10A (0.39) | P2RX7PDE10A | |
| SCHEMBL518823 | 0.83 | P2RX7 (0.40) | P2RX7PDE10A | |
| SCHEMBL519310 | 0.80 | P2RX7 (0.41) | P2RX7PDE10A | |
| SCHEMBL519447 | 0.80 | P2RX7 (0.41) | P2RX7PDE10A | |
| SCHEMBL518617 | 0.77 | P2RX7 (0.39) | P2RX7PDE10A | |
| SCHEMBL519362 | 0.77 | PDE10A (0.73) | PDE10A | |
| SCHEMBL519579 | 0.77 | P2RX7 (0.41) | P2RX7PDE10A | |
| SCHEMBL17677257 | 0.76 | PDE10A (0.46) | P2RX7PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393360-A1 | PYRIDAZINONE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010090737-A1 | PYRIDAZINONE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-12 | — | — | WO | disclosed |