Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311039 | 0.83 | CSNK1D (0.57) | SCN5ACSNK1DCSNK1G2APPALDH1A3 | |
| SCHEMBL16761383 | 0.78 | HDAC4 (0.42) | SCN5AALDH1A3KIF11KDM4EALDH1A1 | |
| SCHEMBL12056714 | 0.75 | SCN5A (0.54) | SCN5AAPPALDH1A3KDM4ENPC1 | |
| SCHEMBL18080888 | 0.74 | SCN5A (0.53) | SCN5AAPPKIF11KDM4ENPC1 | |
| SCHEMBL18443123 | 0.74 | APP (0.54) | CSNK1DCSNK1G2APPALDH1A3AHR | |
| SCHEMBL10053493 | 0.74 | APP (0.54) | CSNK1DCSNK1G2APPALDH1A3AHR | |
| SCHEMBL13469261 | 0.74 | APP (0.50) | CSNK1DCSNK1G2APPALDH1A3AHR | |
| SCHEMBL8812209 | 0.74 | SCN5A (0.53) | SCN5AAPPALDH1A3KDM4ENPC1 | |
| SCHEMBL2118968 | 0.74 | SCN5A (0.53) | SCN5AKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL516957 | 0.74 | PIK3CG (0.55) | SCN5AAPPAHRKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091411-A1 | PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-08-12 | — | — | WO | disclosed |