Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18443123 | 0.78 | APP (0.54) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL10053493 | 0.78 | APP (0.54) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL4897330 | 0.74 | APP (0.47) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL22499286 | 0.74 | APP (0.47) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL4952001 | 0.74 | ALDH1A3 (0.78) | APPALDH1A3ALDH1A1NPC1RAB9A | |
| SCHEMBL10311039 | 0.74 | CSNK1D (0.57) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL10311331 | 0.74 | APP (0.50) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL3782018 | 0.74 | SCN5A (0.49) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL10022395 | 0.74 | APP (0.50) | APPCSNK1DCSNK1G2ALDH1A3AHR | |
| SCHEMBL25774521 | 0.74 | APP (0.47) | APPCSNK1DCSNK1G2ALDH1A3AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263646-A1 | IMAGING AGENTS AND THEIR USE FOR THE DIAGNOSTIC IN VIVO OF NEURODEGENERATIVE DISEASES, NOTABLY ALZHEIMER'S DISEASE AND DERIVATIVE DISEASES | GUERBET (FR) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263646-A1 | IMAGING AGENTS AND THEIR USE FOR THE DIAGNOSTIC IN VIVO OF NEURODEGENERATIVE DISEASES, NOTABLY ALZHEIMER'S DISEASE AND DERIVATIVE DISEASES | SNCA, PSEN2, CLN6 | APP 10/4885CSNK1D 4658/4885CSNK1G2 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.