Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 13/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782488 | 1.00 | SLC6A9 (0.48) | SLC6A9CREBBPIRAK1PFKFB3IRAK4 | |
| SCHEMBL3782491 | 1.00 | SLC6A9 (0.48) | SLC6A9CREBBPIRAK1PFKFB3IRAK4 | |
| SCHEMBL3780203 | 0.87 | SLC6A9 (0.62) | SLC6A9PFKFB3 | |
| SCHEMBL3705038 | 0.83 | SLC6A9 (0.39) | SLC6A9 | |
| SCHEMBL7894946 | 0.83 | SLC6A9 (0.39) | SLC6A9 | |
| SCHEMBL4185907 | 0.83 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4185911 | 0.83 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4186222 | 0.83 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4185910 | 0.83 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4196092 | 0.83 | SLC6A9 (0.36) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |