Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.81 |
| ▸ | PDE5A | O76074 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | USP1 | O94782 | 2/20 | 0.60 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388255 | 0.90 | APP (1.00) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3113122 | 0.90 | APP (1.00) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3106597 | 0.88 | APP (0.85) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL4175973 | 0.88 | CTNNB1 (0.72) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3643055 | 0.86 | PDE5A (0.58) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3113251 | 0.86 | APP (0.81) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3121152 | 0.86 | APP (0.81) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL4174731 | 0.85 | CTNNB1 (0.75) | CTNNB1TCF7L2 | |
| SCHEMBL13929497 | 0.85 | APP (0.70) | APPPDE5AMAPTKMT2ALMNA | |
| SCHEMBL3638414 | 0.85 | APP (0.74) | APPPDE5AMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317607-A1 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2010-12-16 | — | — | US | disclosed |
| CN-101784276-A | Use of compounds for the preparation of antituberculosis agents | SUMMIT CORP PLC | 2010-07-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317607-A1 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | TPX2, DCXR, RRM2 | APP 3840/4885PDE5A 2048/4885MAPT 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.