Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1468391 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8670573 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL30208611 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL31636987 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL10715539 | 0.67 | — | — | |
| Lithium Ion SCHEMBL31634800 | 0.58 | — | — | |
| SCHEMBL29398502 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL7847798 | 0.58 | — | — | |
| SCHEMBL29795443 | 0.58 | — | — | |
| SCHEMBL4049251 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668092-A | BLEND OF ADDITION POLYMERS, METAL-FREE ADDITIVES, EXTREME PRESSURE APPLICATIONS, DRILLING SUBTERRANEAN WELLS, LUBRIANTS FOR JOURNAL BEARINGS | SMITH INTERNATIONAL, INC. (US) | 1997-09-16 | — | — | US | claimed |
| US-7749947-B2 | High performance rock bit grease | SMITH INTERNATIONAL, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20070254817-A1 | High performance rock bit grease | SMITH INTERNATIONAL, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| US-7121365-B2 | Rock bit with grease composition utilizing polarized graphite | SMITH INTERNATIONAL, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050133265-A1 | Rock bit with grease composition utilizing polarized graphite | SMITH INTERNATIONAL INC. | 2005-06-23 | — | — | US | disclosed |
| US-5668092-A | BLEND OF ADDITION POLYMERS, METAL-FREE ADDITIVES, EXTREME PRESSURE APPLICATIONS, DRILLING SUBTERRANEAN WELLS, LUBRIANTS FOR JOURNAL BEARINGS | SMITH INTERNATIONAL, INC. (US) | 1997-09-16 | — | — | US | disclosed |