Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 8/20 | 0.63 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973720 | 0.87 | NR2E1 (0.57) | NR2E1ABL1DDR1DDR2NTRK1 | |
| SCHEMBL24122631 | 0.79 | NR2E1 (0.46) | NR2E1ABL1MALT1DDR1DDR2 | |
| SCHEMBL589390 | 0.77 | NR2E1 (1.00) | NR2E1ABL1 | |
| Hydrochloric Acid SCHEMBL29768795 | 0.76 | NR2E1 (0.97) | NR2E1ABL1 | |
| Hydrochloric Acid SCHEMBL21462041 | 0.76 | NR2E1 (0.97) | NR2E1ABL1 | |
| SCHEMBL29949305 | 0.74 | MAP3K5 (0.38) | NR2E1MAP3K5 | |
| SCHEMBL21887465 | 0.74 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL29404609 | 0.74 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL28848739 | 0.74 | MAP3K5 (0.38) | NR2E1MAP3K5 | |
| SCHEMBL19376626 | 0.74 | NR2E1 (0.64) | NR2E1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096395-A1 | AMIDES AS KINASE INHIBITORS | SYNTECH SOLUTION LLC (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096395-A1 | AMIDES AS KINASE INHIBITORS | SYNTECH SOLUTION LLC (US) | 2010-08-26 | — | — | WO | disclosed |