Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 10/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949305 | 1.00 | MAP3K5 (0.38) | MAP3K5RIPK2GRM5IRAK4GRM1 | |
| SCHEMBL29949355 | 0.82 | CHRNB2 (0.38) | MAP3K5RIPK2 | |
| SCHEMBL28848843 | 0.82 | CHRNB2 (0.38) | MAP3K5RIPK2 | |
| SCHEMBL21887465 | 0.79 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL29404609 | 0.79 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL3783299 | 0.74 | NR2E1 (0.63) | MAP3K5NR2E1 | |
| SCHEMBL28848714 | 0.73 | MAP3K5 (0.42) | MAP3K5GRM5 | |
| SCHEMBL28848844 | 0.71 | MAP3K5 (0.38) | MAP3K5GRM5NR2E1 | |
| SCHEMBL30095423 | 0.69 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL25316032 | 0.68 | NPC1 (0.53) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |