SCHEMBL3783324

SCHEMBL3783324

O=S(=O)(O)c1ncccc1C1=NOCCO1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
ABL1 P00519 1/20 0.32
PLCG1 P19174 1/20 0.32
CES1 P23141 1/20 0.32
PAX8 Q06710 1/20 0.32
RIN1 Q13671 1/20 0.32
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908092 0.86 TDP2 (0.32) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL3776593 0.86 CA1 (0.33) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL8633493 0.80
SCHEMBL13242890 0.77 MKNK1 (0.36)
SCHEMBL15244181 0.76
SCHEMBL13266783 0.74
SCHEMBL19417734 0.74 TDP2 (0.30) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL15805494 0.73 GAA (0.40) KDM4EALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL21860380 0.69 TSHR (0.33) MAPTHTTSMN1; SMN2
SCHEMBL29469898 0.69 CA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010127795-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULFONYL UREAS BAYER CROPSCIENCE AG (DE) 2010-11-11 WO claimed