Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772246 | 0.84 | ESR1 (0.54) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL3510428 | 0.84 | ESR1 (0.54) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL29741666 | 0.82 | MAPT (0.48) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL28661617 | 0.82 | MAPT (0.48) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL18904822 | 0.81 | ACHE (0.43) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL19407290 | 0.81 | ESR1 (0.39) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL2696866 | 0.79 | MAPT (0.50) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL30686705 | 0.79 | MAPT (0.50) | ESR1ESR2EGFRACHEMAPT | |
| Hydrochloric Acid SCHEMBL27337454 | 0.76 | MAPT (0.48) | ESR1ESR2EGFRACHEMAPT | |
| SCHEMBL261141 | 0.76 | ESR1 (0.52) | ESR1ESR2EGFRACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291374-A1 | Composites Comprising Nanoparticles | AJJER LLC (US) | 2010-11-18 | — | — | US | disclosed |