SCHEMBL3785276

SCHEMBL3785276

COc1ccc(C=CC(=O)O)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.57
ATM Q13315 1/20 0.57
MAPT P10636 3/20 0.55
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
GAA P10253 1/20 0.54
JUN P05412 1/20 0.51
NFKB1 P19838 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TNFRSF1A P19438 1/20 0.50
ESR1 P03372 2/20 0.48
HDAC8 Q9BY41 1/20 0.48
PTGS2 P35354 1/20 0.48
LY96 Q9Y6Y9 1/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3785272 1.00 THRB (0.57) THRBATMMAPTALDH1A1MEN1
SCHEMBL3719964 0.87 MAPT (0.55) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL3719966 0.87 MAPT (0.55) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL213132 0.87 THRB (0.44) THRBATMMAPTALDH1A1MEN1
SCHEMBL3896955 0.85 MAPT (0.54) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL3896958 0.85 MAPT (0.54) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL20227828 0.85 MAPT (0.54) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL12473729 0.83 THRB (0.57) THRBATMMAPTALDH1A1MEN1
SCHEMBL15239149 0.83 THRB (0.57) THRBATMMAPTALDH1A1MEN1
SCHEMBL15239365 0.83 THRB (0.57) THRBATMMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107778193-A A kind of preparation method of 2 aminomethyl phenyl azido compound 湖南华腾制药有限公司 2018-03-09 CN claimed
EP-3929635-B1 METHOD FOR MANUFACTURING OPTICALLY ANISOTROPIC FILM LG CHEMICAL LTD (KR) 2024-08-28 EP disclosed
US-12043719-B2 Flame retardant mixture CLARIANT INTERNATIONAL LTD (CH) 2024-07-23 US disclosed
CN-112789532-B Method for producing optically anisotropic film 株式会社LG化学 2023-10-20 CN disclosed
CN-115702216-A Naphthalocyanines and phthalocyanine particles 巴斯夫欧洲公司 2023-02-14 CN disclosed
CN-111033371-B Optical device 株式会社LG化学 2023-01-24 CN disclosed
CN-115485342-A Dithiolene metal complexes 巴斯夫欧洲公司 2022-12-16 CN disclosed
CN-115175958-A Polyolefin compositions 巴斯夫欧洲公司 2022-10-11 CN disclosed
EP-3719566-B1 OPTICAL DEVICE LG CHEMICAL LTD (KR) 2022-10-05 EP disclosed
CN-114786946-A Light stabilizer mixture 巴斯夫欧洲公司 2022-07-22 CN disclosed
WO-1997044316-A9 CATALYTIC ASYMMETRIC AMINOHYDROXYLATION OF OLEFINS WITH SULFONAMIDES 1998-04-09 WO disclosed
US-5700784-A GLYCOSIDES OF HYDROXYSALICYLIC ACID AND/OR GLYCOSIDES OF ESTERS OF HYDROXYSALICYLIC ACID; EXCELLENT WHITENING EFFECT AND SKIN CARE EFFECT SHISEIDO CO., LTD. (JP) 1997-12-23 US disclosed
WO-1997044316-A1 CATALYTIC ASYMMETRIC AMINOHYDROXYLATION OF OLEFINS WITH SULFONAMIDES THE SCRIPPS RESEARCH INSTITUTE (US) 1997-11-27 WO disclosed
WO-1997043230-A1 METHOD FOR ORGANIC REACTIONS LABWELL AB (SE) 1997-11-20 WO disclosed
EP-0511205-B1 PROCESS FOR PRODUCING 2-ETHYLHEXYL-P-METHOXYCINNAMATE ISP VAN DYK INC (US) 1995-01-25 EP disclosed
WO-1993004053-A1 SUBSTITUTED THIAZEPINES AS CENTRAL NERVOUS SYSTEM AGENTS WARNER-LAMBERT COMPANY (US) 1993-03-04 WO disclosed
EP-0511205-A1 PROCESS FOR PRODUCING 2-ETHYLHEXYL-P-METHOXYCINNAMATE. ISP VAN DYK INC (US) 1992-11-04 EP disclosed
US-4970332-A Process for producing 2-ethylhexyl-p-methoxycinnamate MALLINCKRODT, INC. (US) 1990-11-13 US disclosed
WO-1990010617-A1 PROCESS FOR PRODUCING 2-ETHYLHEXYL-P-METHOXYCINNAMATE MALLINCKRODT, INC. (US) 1990-09-20 WO disclosed
EP-0214507-A2 Outdoor films stabilized against chemical attack AMERICAN CYANAMID COMPANY (US) 1987-03-18 EP disclosed