Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.85 |
| ▸ | HRH1 | P35367 | 8/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785505 | 1.00 | HTR6 (0.85) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL3785503 | 1.00 | HTR6 (0.85) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL2186455 | 0.92 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL3026846 | 0.92 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL2186459 | 0.92 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL3034893 | 0.90 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL3034894 | 0.90 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL2191362 | 0.87 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL2191361 | 0.87 | HTR6 (1.00) | HTR6HRH1ADRA2ADRD2HTR2A | |
| SCHEMBL3039535 | 0.86 | HTR6 (0.77) | HTR6HRH1ADRA2ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145887-B1 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM LLC (US) | 2016-04-27 | — | — | EP | claimed |
| EP-2145887-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-01-20 | — | — | EP | claimed |
| EP-2145887-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-01-20 | — | — | EP | disclosed |