Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750976 | 0.95 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL22418959 | 0.88 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL12129656 | 0.86 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL5527671 | 0.86 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL2750529 | 0.86 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL1065165 | 0.86 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL28284855 | 0.86 | CYP2A6 (0.62) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL5527756 | 0.85 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL1935147 | 0.83 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL27799996 | 0.82 | CYP2A6 (0.58) | CYP11B1CYP11B2CYP19A1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445881-B1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | BOE TECHNOLOGY GROUP CO LTD (CN) | 2017-11-15 | — | — | EP | disclosed |
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | CYP4F11, BCL6, CYP2F1 | CYP11B1 19/4885CYP11B2 13/4885CYP19A1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.