Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.60 |
| ▸ | AXL | P30530 | 1/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.60 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418959 | 0.98 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL2750529 | 0.96 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL12129656 | 0.96 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL5527671 | 0.96 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL5527756 | 0.91 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL17177981 | 0.90 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL18682051 | 0.90 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL12129644 | 0.88 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL12576018 | 0.86 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL3785592 | 0.86 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP2A6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445881-B1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | BOE TECHNOLOGY GROUP CO LTD (CN) | 2017-11-15 | — | — | EP | claimed |
| CN-102574794-B | Method for preparing organic compound and organic compound prepared thereby | GENERAL ELECTRIC CO. (US) | 2015-12-16 | — | — | CN | claimed |
| US-8426601-B2 | Process for making organic compounds and the organic compounds made therefrom | GENERAL ELECTRIC COMPANY (US) | 2013-04-23 | — | — | US | claimed |
| US-20120178938-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2012-07-12 | — | — | US | claimed |
| CN-102574794-A | Method for preparing organic compound and organic compound prepared thereby | GEN ELECTRIC | 2012-07-11 | — | — | CN | claimed |
| US-8178682-B2 | Process for making organic compounds and the organic compounds made therefrom | GENERAL ELECTRIC COMPANY (US) | 2012-05-15 | — | — | US | claimed |
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2010-12-30 | — | — | US | claimed |
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| CN-112300134-B | ASK1 inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2023-04-21 | — | — | CN | disclosed |
| US-11133477-B2 | Heterocyclic compound and organic light emitting element using same | LT MATERIALS CO., LTD. (KR) | 2021-09-28 | — | — | US | disclosed |
| US-20020188000-A1 | Imidazo-pyridine derivatives as ligands for gaba receptors | MERCK SHARP & DOHME LTD. (GB) | 2002-12-12 | — | — | US | disclosed |
| EP-1235827-A2 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2002-09-04 | — | — | EP | disclosed |
| WO-2002038568-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-05-16 | — | — | WO | disclosed |
| WO-2001090108-A1 | 3-PHENYL-IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001038326-A2 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-05-31 | — | — | WO | disclosed |
| US-5128335-A | Antibiotics | MERCK & CO., INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0481662-A1 | 2-Heteroarylphenyl-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188000-A1 | Imidazo-pyridine derivatives as ligands for gaba receptors | GABRA3, GABRA2, GABRA1 | CYP11B1 1303/4885CYP11B2 1107/4885CYP2A6 1007/4885 |
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | CYP4F11, BCL6, CYP2F1 | CYP11B1 19/4885CYP11B2 13/4885CYP2A6 41/4885 |
| US-11133477-B2 | Heterocyclic compound and organic light emitting element using same | CRY1, CRY2, CYP1A1 | CYP11B1 53/4885CYP11B2 64/4885CYP2A6 89/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | CYP11B1 4665/4885CYP11B2 4550/4885CYP2A6 4365/4885 |
| US-20120178938-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | CYP2F1, CYP4F2, CYP1B1 | CYP11B1 125/4885CYP11B2 102/4885CYP2A6 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.