SCHEMBL3785870

SCHEMBL3785870

ClC1=C(Cl)C2(Cl)CCC1(Cl)C2(Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
THRB P10828 1/20 0.32
RECQL P46063 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698851 0.61
SCHEMBL128887 0.57
SCHEMBL7628890 0.56 MEN1 (0.38) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL4830344 0.56 MEN1 (0.38) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL7628292 0.54 MEN1 (0.35) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL7628287 0.54 MEN1 (0.35) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL8176504 0.54 MEN1 (0.43) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL3206477 0.52
SCHEMBL8662803 0.52 MEN1 (0.50) MEN1KMT2ATHRBRECQLALDH1A1
SCHEMBL1302787 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3775063-B1 RADIATION CURABLE COMPOSITIONS ALLNEX Belgium SA (BE) 2024-10-09 EP claimed
EP-0057535-B1 FLAME RETARDANT POLYMER SYSTEMS AND COMPOSITIONS OCCIDENTAL CHEMICAL CORPORATION (US) 1985-07-31 EP claimed
JP-2010252673-A CYCLIC DIENIC COMPOUND-DEGRADING MICROORGANISM AND CYCLIC DIENIC COMPOUND-DEGRADING AGENT, APPARATUS FOR CLEANING POLLUTED ENVIRONMENT, AND METHOD FOR DEGRADING CYCLIC DIENIC COMPOUND AND METHOD FOR CLEANING POLLUTION SUBSTANCE NATIONAL INSTITUTE FOR AGRO-ENVIRONMENTAL SCIENCE 2010-11-11 JP disclosed
US-5985275-A β-Lactoglobulin modified with aromatic anhydride compound for preventing HIV infection NEW YORK BLOOD CENTER (US) 1999-11-16 US disclosed
EP-0126216-B1 HYDROXY-T-ALKYL PEROXYESTER PENNWALT CORPORATION (US) 1987-04-08 EP disclosed
US-3804908-A 1,2,3,4,7,7-HEXACHLORO-2-NORBORNENE AND ALPHA,OMEGA-DICHLOROALKANE TELOMERS FROM OCTACHLOROCYCLOPENTENE AND ETHYLENE CONTINENTAL OIL CO 1974-04-16 US disclosed