SCHEMBL7628890

SCHEMBL7628890

ClC1=C(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C1(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628287 0.96 MEN1 (0.35) MEN1KMT2ATDP1THRBRECQL
SCHEMBL7628292 0.96 MEN1 (0.35) MEN1KMT2ATDP1THRBRECQL
SCHEMBL4830344 0.91 MEN1 (0.38) MEN1KMT2ATDP1THRBRECQL
SCHEMBL8662803 0.84 MEN1 (0.50) MEN1KMT2ATDP1THRBRECQL
SCHEMBL7634905 0.84 MEN1 (0.50) MEN1KMT2ATDP1THRBRECQL
SCHEMBL8176504 0.80 MEN1 (0.43) MEN1KMT2ATDP1THRBRECQL
SCHEMBL11703805 0.75 ALDH1A1 (0.35) TDP1ALDH1A1TSHRHIF1A
SCHEMBL5679107 0.75
SCHEMBL8574828 0.70
SCHEMBL8566753 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2654433-A1 SANDPAPER MUTANTS OF BACILLUS AND METHODS OF THEIR USE TO ENHANCE PLANT GROWTH, PROMOTE PLANT HEALTH AND CONTROL DISEASES AND PESTS Bayer Cropscience LP (US) 2013-10-30 EP disclosed
WO-2012087980-A1 SANDPAPER MUTANTS OF BACILLUS AND METHODS OF THEIR USE TO ENHANCE PLANT GROWTH, PROMOTE PLANT HEALTH AND CONTROL DISEASES AND PESTS AGRAQUEST, INC. (US) 2012-06-28 WO disclosed
EP-0913380-B1 PROCESS FOR THE PREPARATION OF FLUORINATED OLEFIN AGENCY IND SCIENCE TECHN (JP) 2002-04-03 EP disclosed
US-6211420-B1 REACTING HALOGENATED OLEFIN WITH ALKALI METAL FLUORIDE IN PRESENCE OF SPECIFIED ORGANIC HALOGEN-CONTAINING COMPOUND TO PRODUCE FLUORINATED OLEFIN JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2001-04-03 US disclosed
EP-0913380-A1 PROCESS FOR THE PREPARATION OF FLUORINATED OLEFIN Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) 1999-05-06 EP disclosed