Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791086 | 1.00 | TSHR (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11802501 | 0.92 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4888226 | 0.91 | HCAR2 (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4889687 | 0.91 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4888287 | 0.91 | HCAR2 (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4893048 | 0.91 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL462001 | 0.88 | TSHR (0.48) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL35576 | 0.88 | ATM (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4889702 | 0.88 | ATM (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11806295 | 0.88 | ALDH1A1 (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056452-A2 | DIMERIC CYANOACRYLATE COMPOUNDS AS RED-SHIFTED UV ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2010-05-20 | — | — | WO | disclosed |