SCHEMBL37862

SCHEMBL37862

O=c1cnc2ccccc2[nH]1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
KDM4E B2RXH2 7/20 0.59
GAA P10253 2/20 0.59
APOBEC3G Q9HC16 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPKAPK2 P49137 1/20 0.56
RPS6KA3 P51812 1/20 0.56
CSNK2A1 P68400 1/20 0.56
PLK3 Q9H4B4 1/20 0.56
ADORA3 P0DMS8 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
PLAUR Q03405 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ABCB11 O95342 1/20 0.45
TP53 P04637 1/20 0.45
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396007 1.00 ALDH1A1 (0.59) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL28029814 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
Bromide SCHEMBL7758533 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
Hydrochloric Acid SCHEMBL20597399 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL31413044 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL30935026 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL11129386 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL30297104 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EGAAAPOBEC3GTDP1
Formaldehyde SCHEMBL27908351 0.96 ALDH1A1 (0.55) ALDH1A1KDM4EGAAAPOBEC3GTDP1
SCHEMBL28863664 0.92 ALDH1A1 (0.52) ALDH1A1KDM4EGAAAPOBEC3GTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3911 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US claimed
CN-120025287-A Method for catalyzing coupling reaction of quinoxalinone and derivative thereof and electrophile by using lithium silicon amide 苏州大学 2025-05-23 CN claimed
CN-119930528-A Heterogeneous synthesis method of chiral quinoxalinone and derivative thereof 深圳连续制药科技有限公司 2025-05-06 CN claimed
CN-119913525-A Electrochemical synthesis method of 3-aryl quinoxalinone compound 新疆大学 2025-05-02 CN claimed
CN-119874694-A Quinoxalinone derivative targeting poly ADP ribose polymerase and androgen receptor, and preparation method and application thereof 无锡市觉新生物科技有限公司 2025-04-25 CN claimed
CN-119663301-A Preparation method and application of C3-cyanoalkyl substituted quinoxalinone 安阳工学院 2025-03-21 CN claimed
CN-119431254-A Deuterated quinoxalinone diaryl methane compound and synthetic method and application thereof 重庆文理学院 2025-02-14 CN claimed
CN-119390699-A Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound 重庆文理学院 2025-02-07 CN claimed
CN-119143683-A Quinoxalinone diaryl methane compound and synthetic method and application thereof 重庆文理学院 2024-12-17 CN claimed
CN-116120246-B 3-Butyl-2 (1H) quinoxalinone compound and preparation method thereof 常州大学 2024-11-19 CN claimed
EP-0429185-A2 Multilayered barrier structures for packaging applications and method for the preparation thereof THE STANDARD OIL COMPANY (US) 1991-05-29 EP claimed
EP-0318294-A2 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS CO., LTD (JP) 1989-05-31 EP claimed
EP-0118982-A1 Organic phosphorous quinoxalinone and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-09-19 EP claimed
EP-0071950-A1 Heteroarylpropanol amines, process for preparing them and medicines containing these compounds Roche Diagnostics GmbH (DE) 1983-02-16 EP claimed
EP-0013751-B1 USE OF QUATERNISED COMPOUNDS IN DYEING PAPER BASF Aktiengesellschaft (DE) 1982-09-15 EP claimed
US-4323362-A CATIONIC DYES BASF AKTIENGESELLSCHAFT (DE) 1982-04-06 US claimed
EP-0029088-A2 Synthesis of 2-keto-1,4-diazacycloalkanes The B.F. GOODRICH Company (US) 1981-05-27 EP claimed
EP-0010426-A1 Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof ELI LILLY AND COMPANY (US) 1980-04-30 EP claimed
EP-0001559-A2 Synthesis of 2-keto-1,4-diazacycloalkanes The B.F. GOODRICH Company (US) 1979-05-02 EP claimed
EP-0001284-A1 UV-light stabilized compositions containing substituted 2-keto-1,4-diazacycloalkanes The B.F. GOODRICH Company (US) 1979-04-04 EP claimed