Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 11/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.48 |
| ▸ | F2 | P00734 | 9/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851656 | 0.95 | ST14 (0.51) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3795204 | 0.90 | ST14 (0.47) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851254 | 0.87 | ST14 (0.52) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851813 | 0.86 | ST14 (0.53) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851558 | 0.85 | MEN1 (0.44) | HDAC1SMPD1 | |
| SCHEMBL851900 | 0.84 | ST14 (0.51) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8509922 | 0.84 | ST14 (0.53) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3786263 | 0.84 | ST14 (0.48) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851365 | 0.84 | ST14 (0.50) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851598 | 0.84 | ST14 (0.57) | ST14PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |