SCHEMBL3786301

SCHEMBL3786301

Nc1cccc(-c2ccccc2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.58
BCL2L1 Q07817 1/20 0.58
HSD17B10 Q99714 1/20 0.58
IKBKB O14920 1/20 0.57
MAOA P21397 1/20 0.56
MAP4K4 O95819 1/20 0.52
ESR2 Q92731 1/20 0.48
PTPN5 P54829 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
BRD4 O60885 2/20 0.47
MAPT P10636 2/20 0.47
MCL1 Q07820 1/20 0.47
NR1I2 O75469 1/20 0.47
SMARCA2 P51531 1/20 0.47
SMARCA4 P51532 1/20 0.47
PBRM1 Q86U86 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3790386 0.86 MAP4K4 (0.50) ALDH1A1HPGDBCL2L1HSD17B10IKBKB
SCHEMBL28447477 0.86 MAP4K4 (0.50) ALDH1A1HPGDBCL2L1HSD17B10IKBKB
SCHEMBL3790537 0.85 MAOA (0.52) ALDH1A1IKBKBMAOAMAP4K4TDP1
SCHEMBL29944266 0.84 HPGD (0.71) ALDH1A1HPGDBCL2L1HSD17B10ESR2
SCHEMBL7570908 0.84 HPGD (0.71) ALDH1A1HPGDBCL2L1HSD17B10ESR2
SCHEMBL29471388 0.84 MAOA (0.68) ALDH1A1HPGDIKBKBMAOAMAP4K4
SCHEMBL2023695 0.84 MAOA (0.68) ALDH1A1HPGDIKBKBMAOAMAP4K4
SCHEMBL3784572 0.83 MCL1 (0.51) ALDH1A1HSD17B10IKBKBMAOAMAP4K4
Hydrochloric Acid SCHEMBL5685035 0.83 MAOA (0.50) ALDH1A1IKBKBMAOAMAP4K4TDP1
SCHEMBL28859739 0.83 IKBKB (0.45) ALDH1A1HPGDBCL2L1HSD17B10IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107093711-B Monodispersed SiOxThe magnanimity preparation method of-C complex microsphere 武汉理工大学 2019-10-25 CN claimed
CN-109942441-A A kind of preparation method of m-aminophenol 上海工程技术大学 2019-06-28 CN claimed
CN-106928160-B A kind of preparation method of cresol-purple perchlorate 大连九信精细化工有限公司 2019-03-05 CN claimed
CN-109199922-A Colouring compositions, colouring method and suitable device 莱雅公司 2019-01-15 CN claimed
CN-109098017-A A kind of reactive dyeing process of cashmere 江苏阳光股份有限公司 2018-12-28 CN claimed
CN-108504349-A A kind of preparation method of rhodamine hydridization carbon dots and the application in mitochondria targets identification 郑州大学 2018-09-07 CN claimed
CN-107080700-A Include the colouring compositions of fatty material, Pyrazolopyridine oxidation base and colour coupler 莱雅公司 2017-08-22 CN claimed
CN-106928160-A A kind of preparation method of cresol-purple perchlorate 大连九信精细化工有限公司 2017-07-07 CN claimed
CN-103491938-B Comprise the oxidative dye compositions of 1 hexyl/heptyl 4,5 diamino-pyrazole and m-aminophenol and its derivant 宝洁公司 2017-03-08 CN claimed
CN-103491937-B Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof 宝洁公司 2016-08-31 CN claimed
CN-1835729-A Tinctorial composition comprising at least one direct dye with mixed chromophores OREAL (FR) 2006-09-20 CN claimed
CN-1203837-C Dye composition containing cationic direct dye and pyraole (1,5-alpha) pyradine as oxidative developing alkali and method of dyeing OREAL (FR) 2005-06-01 CN claimed
CN-1167405-C Keratin fibre dyeing composition containing pyrazolo-(1,5-alpha)-pyrimidine derivatives, dyeing method, pyrazolo-(1,5-alpha) pyrimidine new-type derivatives and preparation method thereof �ź㴫 2004-09-22 CN claimed
CN-1426777-A Composition for oxidation dyeing of keratin fibre and method for dyeing keratin fibre OREAL (FR) 2003-07-02 CN claimed
CN-1300195-A Method for reforming keratin fiber cross-linked product NOVO NORDISK AS (DK) 2001-06-20 CN claimed
CN-1252988-A Dye composition containing cationic direct dye and pyraole (1,5-alpha) pyradine as oxidative developing alkali and method of dyeing OREAL (FR) 2000-05-17 CN claimed
CN-1248577-A Novel cation type 4-oxyindole, its oxidation dyeing, dyeing composition and dyeing method for keration fibre OREAL (FR) 2000-03-29 CN claimed
CN-1196673-A Keratin fibre dyeing composition containing pyrazolo-(1,5-alpha)-pyrimidine derivatives, dyeing method, pyrazolo-(1,5-alpha) pyrimidine new-type derivatives and preparation method thereof OREAL (FR) 1998-10-21 CN claimed
CN-1110048-A Novel 3-substituted para-aminophenols and their use for dyeing keratin fibers OREAL (FR) 1995-10-11 CN claimed
CN-1051670-A Contain the dyeing composition for keratinous fibres of oxidation dye parent and amino indole colour former, the colouring method that uses these compositionss and noval chemical compound OREAL (FR) 1991-05-29 CN claimed