⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188953 | 0.74 | HTR2A (0.48) | — | |
| SCHEMBL9188946 | 0.74 | HTR2A (0.48) | — | |
| SCHEMBL466778 | 0.73 | — | — | |
| SCHEMBL466779 | 0.73 | — | — | |
| SCHEMBL7741970 | 0.71 | — | — | |
| SCHEMBL2398503 | 0.69 | — | — | |
| SCHEMBL24178 | 0.69 | — | — | |
| SCHEMBL7714133 | 0.69 | — | — | |
| SCHEMBL497180 | 0.69 | — | — | |
| SCHEMBL12327087 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340537-A | Quinazoline compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-113698905-A | Flame-retardant silane modified polyether sealant containing DOPO and preparation method thereof | 河北厚丰有机硅制品股份有限公司 | 2021-11-26 | — | — | CN | disclosed |
| US-9921498-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-03-20 | — | — | US | disclosed |
| CN-106749377-A | A kind of N, N are double（Trimethyl silyl）Allyl amine and preparation method thereof | 湖北新蓝天新材料股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-20160377998-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-12-29 | — | — | US | disclosed |
| CN-102149373-B | 1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin diseases | MERZ PHARMA GMBH & CO KGAA | 2012-10-10 | — | — | CN | disclosed |
| CN-102149373-A | 1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin diseases | MERZ PHARMA GMBH & CO KG | 2011-08-10 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-1066448-C | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-05-30 | — | — | CN | disclosed |
| CN-1221419-A | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-06-30 | — | — | CN | disclosed |