⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466778 | 1.00 | — | — | |
| SCHEMBL9188946 | 0.83 | HTR2A (0.48) | — | |
| SCHEMBL9188953 | 0.83 | HTR2A (0.48) | — | |
| SCHEMBL721615 | 0.78 | — | — | |
| SCHEMBL8722833 | 0.77 | — | — | |
| SCHEMBL8722836 | 0.77 | — | — | |
| SCHEMBL20732058 | 0.77 | — | — | |
| SCHEMBL21847765 | 0.75 | HTR2A (0.43) | — | |
| SCHEMBL13679644 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8722822 | 0.75 | GRIK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2574188-A1 | NEW PROCESS FOR THE PREPARATION OF ARYL SUBSTITUTED OLEFINIC AMINES | Targacept, Inc. (US) | 2013-04-03 | — | — | EP | claimed |
| EP-2566476-A1 | NICOTINE-CONTAINING PHARMACEUTICAL COMPOSITIONS | Niconovum USA, Inc. (US) | 2013-03-13 | — | — | EP | claimed |
| WO-2011146009-A1 | NEW PROCESS FOR THE PREPARATION OF ARYL SUBSTITUTED OLEFINIC AMINES | TARGACEPT INC. (SE) | 2011-11-24 | — | — | WO | claimed |
| WO-2011139811-A1 | NICOTINE-CONTAINING PHARMACEUTICAL COMPOSITIONS | NICONOVUM USA, INC. (US) | 2011-11-10 | — | — | WO | claimed |
| CN-112074503-B | Adducts between pyrrole compounds and inorganic oxide hydroxides, superadders, elastomeric compositions comprising superadders and process for their preparation | 倍耐力轮胎股份公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112074503-A | Adducts between pyrrole compounds and inorganic oxide hydroxides, superaddites between pyrrole compounds, inorganic oxide hydroxides and carbon allotropes, elastomeric compositions comprising said superaddites and process for preparing them | 倍耐力轮胎股份公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-109640934-A | Method of increasing the absorption and washfastness of hair health compounds | 宝洁公司 | 2019-04-16 | — | — | CN | disclosed |
| US-8877857-B2 | Polar group-containing copolymer, rubber composition and studless tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| EP-2404944-B1 | POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE | SUMITOMO RUBBER IND (JP) | 2014-05-14 | — | — | EP | disclosed |
| CN-102365306-B | Polar group-containing copolymer, rubber composition and studless tire | SUMITOMO RUBBER IND | 2014-04-02 | — | — | CN | disclosed |
| EP-2574188-A1 | NEW PROCESS FOR THE PREPARATION OF ARYL SUBSTITUTED OLEFINIC AMINES | Targacept, Inc. (US) | 2013-04-03 | — | — | EP | disclosed |
| US-20120095153-A1 | POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-1311265-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | Targacept, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1185514-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | Targacept, Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2002005801-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002005798-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| EP-1086082-A1 | ARYLSUBSTITUTED OLEFINIC AMINES AND THEIR USE AS CHOLINERGIC RECEPTORS AGONISTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-2000075110-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | TARGACEPT, INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-1999065876-A1 | ARYL SUBSTITUTED OLEFINIC AMINES AND THEIR USE AS CHOLINERGIC RECEPTORS AGONISTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| US-5892125-A | REACTING 1,3-BUTADIENE WITH AN AMINE; ISOMERIZATION | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-06 | — | — | US | disclosed |