SCHEMBL3787404

SCHEMBL3787404

CCOC(=O)C(NC(C)=O)C(=O)OCC.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 1/20 0.44
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
SOAT1 P35610 1/20 0.42
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CAD P27708 1/20 0.39
PKM P14618 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
KMT2A Q03164 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332187 0.98 LMNA (0.53) LMNAALDH1A1HSD17B10GAAMGAM
SCHEMBL1331748 0.98 LMNA (0.53) LMNAALDH1A1HSD17B10GAAMGAM
SCHEMBL1330728 0.98 LMNA (0.53) LMNAALDH1A1HSD17B10GAAMGAM
SCHEMBL81193 0.98 LMNA (0.53) LMNAALDH1A1HSD17B10GAAMGAM
SCHEMBL1332017 0.98 LMNA (0.53) LMNAALDH1A1HSD17B10GAAMGAM
Hydrochloric Acid SCHEMBL27898018 0.95 LMNA (0.51) LMNAALDH1A1HSD17B10GAAMGAM
Alcohol SCHEMBL27600744 0.93 LMNA (0.50) LMNAALDH1A1HSD17B10GAAMGAM
Acetic Acid SCHEMBL27299232 0.93 LMNA (0.50) LMNAALDH1A1HSD17B10GAAMGAM
SCHEMBL16727820 0.91 LMNA (0.49) LMNAALDH1A1HSD17B10GAAMGAM
Acetic Acid SCHEMBL27475348 0.91 LMNA (0.49) LMNAALDH1A1HSD17B10GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3112340-B1 METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO, AND PRECURSOR OF 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO STELLA PHARMA CORP (JP) 2020-07-15 EP disclosed
CN-102887913-B Method for synthesizing 4-dihydroxyborane-2-fluorophenylalanine NANJING PET TRACER CO LTD 2015-02-25 CN disclosed
CN-102887913-A Method for synthesizing 4-dihydroxyborane-2-fluorophenylalanine NANJING PET TRACER CO LTD 2013-01-23 CN disclosed
US-7662572-B2 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC. (US) 2010-02-16 US disclosed
US-20070099249-A1 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2007-05-03 US disclosed
WO-2007025129-A2 COMPOSITIONS AND LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC. (US) 2007-03-01 WO disclosed
CN-1198839-C Novel dipeptide amidines as thrombin inhibitors AIBET GMBH & CO KG (DE) 2005-04-27 CN disclosed
CN-1175953-A Novel dipeptide amidines as thrombin inhibitors BASF AG (DE) 1998-03-11 CN disclosed
US-5565480-A ANGIOTENSIN II RECEPTOR ANTAGONIST; USEFUL IN REGULATING HYPERTENSION, TREATMENT OF CONGESTIVE HEART FAILURE, RENAL FAILURE AND GLUCOMA SMITHKLINE BEECHAM CORPORATION (US) 1996-10-15 US disclosed
US-5444081-A Treatment of hypertension, congestive heart failure, renal failure, glaucoma SMITHKLINE BEECHAM CORP (US) 1995-08-22 US disclosed
US-5395827-A Analgesic, anticonvulsant, antiepileptic and anxiolytic agents GUILFORD PHARMACEUTICALS INC. (US) 1995-03-07 US disclosed
WO-1993005772-A1 φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS NOVA PHARMACEUTICAL CORPORATION (US) 1993-04-01 WO disclosed
US-4483853-A ANTICONVULSANTS COLLINS JAMES F 1984-11-20 US disclosed
US-4477391-A Amino acid isomers, their production and their medicinal use COLLINS JAMES F (GB) 1984-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099249-A1 Compositions and liquid crystals FABP5, FABP1, SSB LMNA 283/4885ALDH1A1 4540/4885HSD17B10 1353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.