Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.67 |
| ▸ | DRD2 | P14416 | 18/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378700 | 1.00 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL12313269 | 1.00 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL11914878 | 1.00 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL378740 | 1.00 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL11911794 | 1.00 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL378630 | 0.90 | DRD2 (0.68) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| Hydrochloric Acid SCHEMBL4433075 | 0.90 | DRD2 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| Hydrochloric Acid SCHEMBL4551295 | 0.90 | DRD2 (0.67) | DRD3KCNH2DRD2CYP1A2CHRM1 | |
| SCHEMBL378474 | 0.87 | KCNH2 (0.64) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL378310 | 0.86 | KCNH2 (0.63) | DRD3KCNH2DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060570-B1 | Azabicyclo[3.1.0] hexane derivatives useful as modulators of dopamine D3 receptors | GLAXO GROUP LTD (GB) | 2012-01-25 | — | — | EP | claimed |