Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324177 | 0.77 | MAOB (0.44) | MAOAMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL5750514 | 0.75 | KDM4E (0.34) | MAOAMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL24245 | 0.75 | APP (0.35) | SMN1; SMN2RAB9ANPC1NQO1NQO2 | |
| SCHEMBL3049744 | 0.69 | PRKDC (0.47) | MAOAMAOBMAPTRAB9ANPC1 | |
| SCHEMBL29513414 | 0.69 | PRKDC (0.47) | MAOAMAOBMAPTRAB9ANPC1 | |
| SCHEMBL28092391 | 0.69 | NQO1 (0.44) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL13229114 | 0.65 | MAOB (0.43) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL30442156 | 0.65 | NPC1 (0.39) | MAOAMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL29710475 | 0.63 | APP (0.54) | MAOAMAOBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21313231 | 0.63 | NPC1 (0.39) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842677-B2 | Synthetic ganglioside derivatives and compositions thereof | SENEB BIOSCIENCES, INC. (US) | 2010-11-30 | — | — | US | disclosed |
| US-20050239741-A1 | Novel synthetic ganglioside derivatives and compositions thereof | LA JOLLA PHARMACEUTICAL COMPANY | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239741-A1 | Novel synthetic ganglioside derivatives and compositions thereof | SGMS2, GBA1, SGMS1 | MAOA 2285/4885MAOB 1422/4885ALDH1A1 3685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.