Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665372 | 1.00 | POLB (0.59) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL3777075 | 1.00 | POLB (0.59) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL27495 | 1.00 | POLB (0.59) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL572756 | 1.00 | POLB (0.59) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL721693 | 0.87 | POLB (0.74) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| Alanine SCHEMBL15656219 | 0.86 | POLB (0.48) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL23287488 | 0.86 | POLB (0.70) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL381246 | 0.86 | POLB (0.70) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL713506 | 0.86 | POLB (0.70) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL24062391 | 0.86 | POLB (0.70) | POLBALDH1A1SMN1; SMN2TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795370-B2 | Tetracarboxylic acid compound, polyimide thereof, and production method thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20090182114-A1 | TETRACARBOXYLIC ACID COMPOUND, POLYIMIDE THEREOF, AND PRODUCTION METHOD THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20050233149-A1 | Curable compositions | ANSELL CHRISTOPHER | 2005-10-20 | — | — | US | disclosed |
| EP-0885405-B1 | PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS | SUMITOMO BAKELITE CO (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-1056538-B1 | ACID ACTIVATION OF RUTHENIUM METATHESIS CATALYSTS AND LIVING ROMP METATHESIS POLYMERIZATION IN WATER | CALIFORNIA INST OF TECHN (US) | 2005-04-20 | — | — | EP | disclosed |
| CN-1198181-C | Photoresist compositions comprising polycyclic polymers with acid labile pendant groups | SUMITOMO BAKELITE CO (JP) | 2005-04-20 | — | — | CN | disclosed |
| US-6790579-B1 | PHOTOACID INITIATOR GENERATES ACID EFFECTING POLARITY CHANGE RENDERING POLYMER WATER SOLUBLE IN AREAS EXPOSED TO IMAGING SOURCE; INTEGRATED CIRCUITS, SEMICONDUCTORS | SUMITOMO BAKELITE CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20040151902-A1 | Curable compositions | ANSELL CHRISTOPHER (GB) | 2004-08-05 | — | — | US | disclosed |
| US-6723486-B2 | POLYMERIZING AT LEAST TWO TYPES OF POLYCYCLIC (NORBORNENE) MONOMERS ONE OF WHICH CONTAINING A PENDANT ACID LABILE GROUP AND ANOTHER OF WHICH CONTAINING A PENDNT POLAR FUNCTIONAL GROUP USING A GROUP 8 TRANSITION METAL CATALYST | SUMITOMO BAKELITE CO., LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1056538-A4 | ACID ACTIVATION OF RUTHENIUM METATHESIS CATALYSTS AND LIVING ROMP METATHESIS POLYMERIZATION IN WATER | CALIFORNIA INST OF TECHN (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-0544843-A1 | HINDERED PHENOLIC NORBORNENE DICARBOXIMIDE | MONSANTO COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003418-A1 | HINDERED PHENOLIC NORBORNENE DICARBOXIMIDE | MONSANTO COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4647585-A | Bicycloheptane substituted ethers | E. R. SQUIBB & SONS, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| US-4542160-A | Method of use of bicycloheptane substituted prostaglandin analogs as cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1985-09-17 | — | — | US | disclosed |
| US-4126738-A | Copolymers of 5-norbornene 2,3-dicarboxylic anhydride and maleic anhydride | BORG-WARNER CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |
| US-4018767-A | 5-ENDO-(1-NAPHTHOYLOXY)-N-(AMINOALKYL) BICYCLO(2.2.1)HEPTANE-2,3-DI-ENDO-CARBOXYLIC ACID IMIDES | BRISTOL-MYERS COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4012575-A | Homopolymers of cis-5-norbornene-2,3-dicarboxylic anhydrides | BORG-WARNER CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3995099-A | Copolymers of endo and exo cis-5-norbornene-2,3-dicarboxylic anhydrides | LINDAU CHEMICALS, INC., A CORP. OF SC | 1976-11-30 | — | — | US | disclosed |
| US-3980668-A | Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides | BRISTOL-MYERS COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3936449-A | 5-ENDO-CARBAMOYLOXY-N-(AMINO(LOWER)-ALKYL)BICYCLO(2.2.1)HEPTANE-2,3 -DI-ENDO-CARBOXYLIC ACID IMIDES | Ohki, Sadao (JA) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182114-A1 | TETRACARBOXYLIC ACID COMPOUND, POLYIMIDE THEREOF, AND PRODUCTION METHOD THEREOF | CA1, TTC14, F12 | POLB 3322/4885ALDH1A1 2803/4885SMN1; SMN2 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.