Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406152 | 0.85 | GAA (0.49) | GAALMNAPOLBSTING1CYP2C19 | |
| SCHEMBL27596801 | 0.85 | GAA (0.49) | GAALMNAPOLBCYP2C19CYP3A4 | |
| SCHEMBL3730626 | 0.84 | GAA (0.48) | GAALMNAPOLBCYP2C19CYP3A4 | |
| SCHEMBL27615388 | 0.81 | GAA (0.49) | GAALMNAPOLBCYP2C19CYP3A4 | |
| SCHEMBL7555630 | 0.80 | GAA (0.48) | GAALMNAPOLBALDH1A1KDM4E | |
| SCHEMBL16703727 | 0.76 | ADORA2A (0.38) | GAAALDH1A1KDM4EADORA2AADORA1 | |
| SCHEMBL3150975 | 0.75 | NPC1 (0.56) | GAALMNAPOLBCYP2C19CYP1A2 | |
| SCHEMBL970933 | 0.75 | GAA (0.55) | GAALMNAPOLBSTING1CYP2C19 | |
| SCHEMBL2576002 | 0.74 | IRAK4 (0.33) | GAAADORA2AADORA1 | |
| SCHEMBL16105736 | 0.74 | GAA (0.42) | GAALMNAPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235005-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009077500-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |