SCHEMBL970933

SCHEMBL970933

Cn1cc(C(N)=O)c(C(F)(F)F)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.55
LMNA P02545 2/20 0.54
POLB P06746 1/20 0.54
STING1 Q86WV6 1/20 0.47
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38
PSENEN Q9NZ42 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
BACE1 P56817 2/20 0.37
BACE2 Q9Y5Z0 2/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
NTRK1 P04629 1/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29451179 0.86 LMNA (0.45) GAALMNAPOLBSTING1PSEN1
SCHEMBL27714203 0.85 GAA (0.46) GAALMNAPOLBSTING1NPC1
SCHEMBL19182678 0.84 GAA (0.56) GAALMNAPOLBSTING1PSEN1
SCHEMBL353314 0.84 GAA (0.56) GAALMNAPOLBSTING1PSEN1
SCHEMBL13936345 0.84 POLB (0.58) GAALMNAPOLBSTING1PSEN1
SCHEMBL28114507 0.83 LMNA (0.62) GAALMNAPOLBSTING1BACE1
SCHEMBL974230 0.82 LMNA (0.57) GAALMNAPOLBSTING1PSEN1
SCHEMBL4556189 0.82 GAA (0.55) GAALMNAPOLBSTING1PSEN1
SCHEMBL17350744 0.82 GAA (0.55) GAALMNAPOLBSTING1PSEN1
Hydrochloric Acid SCHEMBL8355477 0.82 GAA (0.55) GAALMNAPOLBSTING1PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773327-B Preparation method of penthiopyrad intermediate 广东优康精细化工有限公司 2023-08-18 CN claimed
CN-114264743-B Detection method of animal-derived substrate penthiopyrad and metabolite thereof 中国科学院动物研究所 2022-11-29 CN claimed
CN-114773327-A Preparation method of penthiopyrad intermediate 广东优康精细化工有限公司 2022-07-22 CN claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
CN-101184391-B Substance combinations with synergistic fungicidal activity BAYER CROPSCIENCE AG 2013-07-24 CN claimed
US-12433291-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2025-10-07 US disclosed
CN-116250545-B Bacillus amyloliquefaciens FCC1256 compositions and methods of controlling plant pathogens FMC公司 2025-05-09 CN disclosed
CN-117269341-B Method for detecting penthiopyrad and metabolite thereof in animal-derived food 广州海关技术中心 2025-04-08 CN disclosed
CN-119569655-A Pyrazolecarboxamide-containing fluorine methyl thioester benzoate compound and preparation method and application thereof 西北大学 2025-03-07 CN disclosed
WO-2024155782-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PLANT PATHOGENS KANNAR EARTH SCIENCE, LTD. (US) 2024-07-25 WO disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 CN disclosed
CN-117603140-A Pyrazole acyl urea or thiourea compound containing substituted biphenyl structure, and preparation method and application thereof 浙江树人学院 2024-02-27 CN disclosed
US-20040077557-A1 Macrolide antibiotics GLAXO GROUP LIMITED (GB) 2004-04-22 US disclosed
CN-1142929-C Process for producing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative ������ѧ��ʽ���� 2004-03-24 CN disclosed
EP-1363925-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2003-11-26 EP disclosed
WO-2002050091-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2002-06-27 WO disclosed
CN-1338452-A Substituted phenylamine derivatives MITSUI CHEMICALS INC (JP) 2002-03-06 CN disclosed
CN-1067063-C Substituted carboxanilide derivatives and plant disease control agents containing the same as active ingredient MITSUI TOATSU CHEMICALS (JP) 2001-06-13 CN disclosed
CN-1267671-A Process for producing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative MITSUI CHEMICALS INC (JP) 2000-09-27 CN disclosed
CN-1178791-A Substituted carboxanilide derivatives and plant disease control agents containing the same as active ingredient MITSUI TOATSU CHEMICALS (JP) 1998-04-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077557-A1 Macrolide antibiotics MALT1, MRPL21, IL1R1 GAA 584/4885LMNA 1504/4885POLB 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.