Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202066 | 0.76 | APOBEC3A (0.47) | PDPK1RAB9AKDRADRA2AADRA1A | |
| SCHEMBL29846190 | 0.76 | PDPK1 (0.41) | PDPK1RAB9AKDRHSP90AA1SYK | |
| SCHEMBL16863346 | 0.75 | KDM4E (0.43) | RAB9AMIFKDM4EHSD17B10HRH3 | |
| SCHEMBL11322916 | 0.73 | KDM4E (0.50) | RAB9AMIFKDM4EHSD17B10HRH3 | |
| SCHEMBL29846161 | 0.73 | MIF (0.36) | RAB9AMIFKDM4EHSD17B10HRH3 | |
| SCHEMBL5953401 | 0.72 | HRH3 (0.51) | RAB9AMIFKDM4EHSD17B10HRH3 | |
| SCHEMBL31024123 | 0.70 | HRH3 (0.47) | MIFKDM4EHRH3MAP4K4ABL1 | |
| SCHEMBL7169834 | 0.69 | PDPK1 (0.51) | PDPK1RAB9AKDRADRA2AADRA1A | |
| SCHEMBL16265168 | 0.68 | DYRK1A (0.54) | PDPK1RAB9AKDRADRA2AADRA1A | |
| SCHEMBL3957689 | 0.67 | MAP4K4 (0.41) | RAB9AMIFKDM4EHSD17B10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025143152-A1 | THIAZOLYL-PYRAZOLO[1,5-A]PYRIDINE COMPOUND AND USE THEREOF AS MYLK4 INHIBITOR | 全薬工業株式会社 | 2025-07-03 | — | — | WO | disclosed |
| EP-2391619-A1 | HETEROARYLS AND THEIR USE AS PI3K INHIBITORS | Millennium Pharmaceuticals, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010090716-A1 | HETEROARYLS AND THEIR USE AS PI3K INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |