Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788863 | 1.00 | PRKCA (0.56) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL4213443 | 0.89 | PRKCA (0.54) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL394439 | 0.87 | PRKCA (0.57) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3079634 | 0.85 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3080762 | 0.85 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL2280300 | 0.82 | PRKCA (0.47) | PRKCAMMP12NR1I2SCN9A | |
| SCHEMBL2280297 | 0.81 | PRKCA (0.46) | PRKCAMMP12NR1I2SCN9A | |
| SCHEMBL3086850 | 0.80 | PRKCA (0.57) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL4221755 | 0.79 | PRKCA (0.53) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL4830061 | 0.78 | PRKCA (0.55) | PRKCAMMP12NR1I2SCN9AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082050-A1 | MACROCYCLIC AND 7-AMINOALKYL-SUBSTITUTED BENZOXAZOCINES FOR TREATMENT OF HEPATITIS C INFECTIONS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-07-22 | — | — | WO | disclosed |