Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.55 |
| ▸ | CA2 | P00918 | 11/20 | 0.55 |
| ▸ | CA9 | Q16790 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL11414843 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL8343031 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11028488 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11580345 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11580773 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL28720260 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL430867 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL428820 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL7588149 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL3963770 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470756-B2 | Eco-friendly laundry pretreatment compositions | S.C. JOHNSON & SON, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| EP-2408887-A1 | ECO-FRIENDLY LAUNDRY PRETREATMENT COMPOSITIONS | S.C. Johnson & Son, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107489-A1 | ECO-FRIENDLY LAUNDRY PRETREATMENT COMPOSITIONS | S. C. JOHNSON & SON, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100144580-A1 | Eco-Friendly Laundry Pretreatment Compositions | S.C. JOHNSON & SON, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-5880076-A | PERSONAL PRODUCT OR DETERGENT COMPOSITION COMPRISING CYCLIC GLYCACARBAMATE AND/OR GLYCAUREA, SURFACTANT | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5653970-A | CLEANING COMPOUNDS; COSMETICS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5641480-A | ENHANCED STABILITY AND/OR VISCOSITY, CLARITY | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| US-5624906-A | Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-04-29 | — | — | US | disclosed |