Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.55 |
| ▸ | CA2 | P00918 | 11/20 | 0.55 |
| ▸ | CA9 | Q16790 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL11414843 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL8343031 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11028488 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL378930 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11580345 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL11580773 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL28720260 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL430867 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Monoethanolamine SCHEMBL7588149 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL3963770 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019109243-A1 | Cosmetic composition for permanently changing the shape of keratinous fibers | HENKEL AG & CO.KGAA (DE) | 2019-06-13 | — | — | WO | disclosed |
| EP-2136768-B1 | STRUCTURED SURFACTANT COMPOSITIONS | SOLVAY USA INC (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-2419077-B1 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2016-10-12 | — | — | EP | disclosed |
| EP-2393469-B1 | Process of treating hair | RHODIA OPERATIONS (FR) | 2016-10-12 | — | — | EP | disclosed |
| US-20140308227-A1 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2014-10-16 | — | — | US | disclosed |
| US-8828364-B2 | Structured surfactant compositions | RHODIA OPERATIONS (FR) | 2014-09-09 | — | — | US | disclosed |
| EP-2419077-A2 | PROCESS OF TREATING DAMAGED HAIR | Rhodia Opérations (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120021025-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2012-01-26 | — | — | US | disclosed |
| WO-2010089228-A9 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2011-04-21 | — | — | WO | disclosed |
| WO-2010118925-A2 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010089228-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2010-08-12 | — | — | WO | disclosed |
| EP-2216010-A1 | Aqueous composition suitable as shampoo | Rhodia Opérations (FR) | 2010-08-11 | — | — | EP | disclosed |
| EP-2136768-A1 | STRUCTURED SURFACTANT COMPOSITIONS | Rhodia, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008118381-A1 | STRUCTURED SURFACTANT COMPOSITIONS | RHODIA INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20080233061-A1 | Alkyl ether sulfate surfactant, alkyl sulfate surfactant, alkanolamide surfactant,amphoteric surfactant, and electrolyte; opacity, yield strength; sodium trideceth sulfate, sodium lauryl sulfate, ammonium lauryl sulfate, sodium lauroamphoacetate, coco monoethanolamide, ammonium chloride, citric acid | SPECIALTY OPERATIONS FRANCE (FR) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233061-A1 | Alkyl ether sulfate surfactant, alkyl sulfate surfactant, alkanolamide surfactant,amphoteric surfactant, and electrolyte; opacity, yield strength; sodium trideceth sulfate, sodium lauryl sulfate, ammonium lauryl sulfate, sodium lauroamphoacetate, coco monoethanolamide, ammonium chloride, citric acid | SGMS2, SGMS1, ACMSD | CA1 100/4885CA2 13/4885CA9 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.