Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 15/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189005 | 0.84 | TRPM8 (0.78) | TRPM8TRPV1 | |
| SCHEMBL3794698 | 0.82 | TRPM8 (0.70) | TRPM8TRPV1 | |
| SCHEMBL3803441 | 0.81 | TRPM8 (0.55) | TRPM8TRPV1SCD | |
| SCHEMBL3796860 | 0.78 | TRPM8 (0.53) | TRPM8TRPV1SCD | |
| SCHEMBL537650 | 0.74 | TRPM8 (0.64) | TRPM8TRPV1SCD | |
| SCHEMBL3713990 | 0.73 | TRPM8 (0.53) | TRPM8TRPV1 | |
| SCHEMBL1691354 | 0.70 | TRPM8 (0.59) | TRPM8TRPV1 | |
| SCHEMBL13188827 | 0.70 | TRPM8 (1.00) | TRPM8TRPV1 | |
| SCHEMBL3794699 | 0.69 | TRPM8 (0.50) | TRPM8TRPV1 | |
| SCHEMBL13188131 | 0.68 | TRPM8 (1.00) | TRPM8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103381-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES AS TRPM 8 MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-09-16 | — | — | WO | claimed |