Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.41 |
| ▸ | NAMPT | P43490 | 7/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785767 | 0.88 | EPHX2 (0.42) | DDR1NAMPTSCN5A | |
| SCHEMBL13258581 | 0.83 | SCN5A (0.43) | DDR1SCN5A | |
| SCHEMBL3791650 | 0.83 | EPHX2 (0.54) | DDR1SCN5A | |
| SCHEMBL3787257 | 0.83 | DDR1 (0.39) | DDR1NAMPT | |
| SCHEMBL3787856 | 0.82 | NAMPT (0.38) | DDR1NAMPT | |
| SCHEMBL3785014 | 0.81 | DDR1 (0.46) | DDR1NAMPT | |
| SCHEMBL3791622 | 0.81 | EPHX2 (0.51) | SCN5A | |
| SCHEMBL3790038 | 0.81 | EPHX2 (0.52) | SCN5A | |
| SCHEMBL3792943 | 0.80 | EPHX2 (0.42) | DDR1SCN5A | |
| SCHEMBL3788739 | 0.80 | DDR1 (0.37) | DDR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |