SCHEMBL378958

SCHEMBL378958

Cn1cc(C=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
IMPDH2 P12268 1/20 1.00
KDM4E B2RXH2 4/20 0.59
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
MAPT P10636 4/20 0.55
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.55
CASP3 P42574 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
CRHBP P24387 1/20 0.55
CRHR2 Q13324 1/20 0.55
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TP53 P04637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365374 1.00 ALDH1A1 (1.00) ALDH1A1IMPDH2KDM4EKMT2AMEN1
Water SCHEMBL27751444 0.98 ALDH1A1 (0.96) ALDH1A1IMPDH2KDM4EKMT2AMEN1
Fluorobenzene SCHEMBL27749295 0.90 ALDH1A1 (0.81) ALDH1A1IMPDH2KDM4EKMT2AMEN1
Chlorobenzene SCHEMBL28774129 0.90 ALDH1A1 (0.81) ALDH1A1IMPDH2KDM4EKMT2AMEN1
Bromobenzene SCHEMBL27728887 0.90 ALDH1A1 (0.81) ALDH1A1IMPDH2KDM4EKMT2AMEN1
SCHEMBL7529789 0.88 ALDH1A1 (0.78) ALDH1A1IMPDH2KDM4EKMT2AMEN1
SCHEMBL29577068 0.87 ALDH1A1 (0.77) ALDH1A1IMPDH2KDM4EKMT2AMEN1
SCHEMBL11096672 0.87 ALDH1A1 (0.77) ALDH1A1IMPDH2KDM4EKMT2AMEN1
Glycine SCHEMBL8212710 0.86 ALDH1A1 (0.73) ALDH1A1IMPDH2KDM4EKMT2AMEN1
SCHEMBL3866851 0.86 ALDH1A1 (0.73) ALDH1A1IMPDH2KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-117229194-A One-pot two-step lignin-based carbazole derivative synthesis method 中国科学院大连化学物理研究所 2023-12-15 CN claimed
CN-116574048-A Bromination reaction method of remote indole C-H bond by using sunlight catalysis 陕西科技大学 2023-08-11 CN claimed
CN-110790695-B Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2023-04-11 CN claimed
CN-108353906-B Application of indole-3-formaldehyde and derivatives thereof in preventing and treating plant diseases caused by plant pathogenic fungi 华南农业大学 2021-04-23 CN claimed
CN-110790695-A Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2020-02-14 CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 EP claimed
US-8268015-B2 Method for decolorizing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2012-09-18 US claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed
EP-0873744-A2 Use of heterocyclic carbonyl compounds for dying keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed