Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | CDC25B | P30305 | 5/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784417 | 0.90 | PPARA (0.52) | HDAC1ACEPTPN1CDC25BPTPN2 | |
| SCHEMBL304588 | 0.87 | ACE (0.56) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL3331695 | 0.87 | ACE (0.56) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL3788273 | 0.79 | MDM2 (0.57) | HDAC1 | |
| SCHEMBL26347313 | 0.78 | ACE (0.49) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL29034539 | 0.78 | ACE (0.49) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL3784370 | 0.78 | PTPN1 (0.42) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL305197 | 0.78 | CYP19A1 (0.49) | HDAC1 | |
| SCHEMBL756405 | 0.77 | PTPN1 (0.49) | ACEPTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL10132030 | 0.77 | PTPN1 (0.49) | ACEPTPN1CDC25BPTPN2CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210882-A1 | Synthesis of new protected azahistidine, their processes and their use in synthesises | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081882-A2 | SYNTHESIS OF NEW PROTECTED AZAHISTIDINES, THEIR PROCESSES AND THEIR USE IN SYNTHESISES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2010-07-22 | — | — | WO | disclosed |